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Diabetes insipidus is rare in cats and is characterized by excessive drinking and the production of enormous volumes of extremely dilute urine. Despite drinking large volumes of water, the cat can become dehydrated from urinating so much. Increased drinking and urination are common signs of several other health conditions, so it is essential that several diagnostic tests be performed to diagnose diabetes insipidus. While the condition is rarely curable, it is usually successfully controlled.
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Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.
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Diabetes mellitus is a disease of the pancreas. This small organ located near the stomach has two different types of cells that have very different functions. One group of cells produces the enzymes necessary for proper digestion.
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This handout provides general information about diabetes mellitus in dogs. For information about its treatment, see the fact sheets "Diabetes Mellitus - Principles of Treatment" and "Diabetes Mellitus - Insulin Treatment".
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This handout provides detailed information on insulin administration. For more information about diabetes mellitus, see the fact sheets "Diabetes Mellitus - General Information", and "Diabetes Mellitus - Principles of Treatment".
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This handout provides detailed information on the principles of treatment in diabetes mellitus. For more information about diabetes mellitus and its treatment, see the fact sheets "Diabetes Mellitus - General Information", and "Diabetes Mellitus - Insulin Treatment".
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Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.
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New medications can help regulate blood glucose levels in cats, including once-daily oral medications bexagliflozin (Bexacat) and velagliflozin (Senvelgo). Cats in the initial stages of DM may benefit most from oral diabetes treatments. This article discusses how these medications work, potential risks, and monitoring required.
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Diabetes mellitus is an inability to regulate blood glucose caused by a loss of insulin production (Type I) or inadequate insulin supply or resistance (Type II). In cats, diabetes mellitus is most often type II. This type of diabetes usually results from obesity, creating insulin resistance. Cats with type II may be treated with oral medication, but some cats may ultimately require insulin injections. Diet is also important. This article discusses various treatments and monitoring regimens.
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Diabetic ketoacidosis is a medical emergency that occurs when there is not enough insulin, or the available insulin isn’t effective enough to control blood sugar (glucose) levels. Your veterinarian needs to perform appropriate tests to diagnose this disease, as similar signs can occur with other medical conditions. Treatment involves hospitalization with IV fluids, short-acting insulin and electrolyte replacement. The most important step in prevention is ensuring careful insulin dosing and disease monitoring.